Start out going southeast on Union Church Rd/VA-646 toward Miller Camp Rd/VA-691.
Turn left onto Miller Camp Rd/VA-691.
Turn right onto VA-24/Mount Rush Hwy. Continue to follow VA-24.
Stay straight to go onto Old Courthouse Rd/VA-24.
Merge onto US-460 W toward Lynchburg.
US-460 W becomes Richmond Hwy.
Stay straight to go onto US-460 W/Richmond Hwy. Continue to follow US-460 W.
Turn right onto Cloverdale Rd/US-220 Alt N.
Cloverdale Rd/US-220 Alt N becomes US-220 N/Roanoke Rd.
Merge onto I-81 S toward US-220 S/Roanoke.
Keep left to take I-81 S toward Bristol (Crossing into Tennessee).
Merge onto I-40 W via EXIT 1B toward Knoxville.
Keep left to take I-75 S via EXIT 368 toward Chattanooga.
Merge onto I-24 W via EXIT 2 toward I-59/Chattanooga/Birmingham (Crossing into Georgia).
Merge onto I-59 S via EXIT 167 on the left toward Birmingham (Crossing into Alabama).
Merge onto I-459 S via EXIT 137 on the left toward Tuscaloosa/Montgomery.
Merge onto I-59 S via the exit on the left toward Tuscaloosa (Passing through Mississippi, then crossing into Louisiana).
Merge onto I-12 W via EXIT 1A toward Hammond.
Merge onto I-10 W via the exit on the left.
Keep left to take I-10 W toward Lafayette (Crossing into Texas).
Merge onto TX-8 N/E Sam Houston Tollway N via EXIT 781A toward Sam Houston Pkwy.
Take the exit toward Wallisville Rd.
Merge onto E Sam Houston Pkwy N.
Turn left onto Wallisville Rd.
Turn left onto Uvalde Rd.
12 UVALDE RD is on the right.